Run order

HP-β-CD (molar ratio)

Avicel PH 102 (%)

SSG (%)

CPVP (%)

CCS (%)

SS (%)

Va (%)

CSD

(%)

MgS (%)

Assay

(n = 3)

±SD

Parameters

DT (sec)

Dissolution (%)

F1

2

40

2

2

5

4

0.5

0.5

1.5

100.97

1.27

107

98.53

F2

2

40

8

5

1

4

0.1

0.5

0.5

100.59

0.57

70

101.57

F3

0.5

60

2

2

1

4

0.5

1.5

0.5

99.94

1.65

214

90.53

F4

0.5

60

8

2

5

2

0.1

0.5

1.5

99.93

2.34

41

93.67

F5

2

60

8

2

5

4

0.1

1.5

0.5

99.95

1.42

44

101.2

F6

0.5

40

2

2

1

2

0.1

0.5

0.5

99.61

0.62

205

90.12

F7

2

40

8

2

1

2

0.5

1.5

1.5

99.47

0.96

75

100.4

F8

0.5

40

8

5

5

2

0.5

1.5

0.5

98.66

1.37

40

93.10

F9

2

60

2

5

5

2

0.5

0.5

0.5

99.80

0.50

50

99.5

F10

2

60

2

5

1

2

0.1

1.5

1.5

100.16

1.17

76

98.12

F11

0.5

60

8

5

1

4

0.5

0.5

1.5

100.21

1.19

46

94.14

F12

0.5

40

2

5

5

4

0.1

1.5

1.5

98.58

1.2

100

92.80